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Human Rad51 filaments on double- and one-stranded DNA: correlating typical and irregular sorts with recombination perform.
[Laughs] ‘It had been absolutely a terrific possibility! At enough time, I used to be effectively conscious that it could go Incorrect and that I could become significantly less prosperous, but I just overlooked that. Curiosity has constantly been my strongest driving power. And luckily everything labored out.’
Sculpting nano-electrodes by using a transmission electron beam for electrical and geometrical characterization of nanoparticles.
De sterke polarisatie in de discussie rond schepping/evolutie en meer algemeen rond geloof/wetenschap lijkt helaas geen eind te kennen. Toch is er wel degelijk een heilzame middenweg, maar deze krijgt above het algemeen weinig aandacht. Dit boek kan hier wellicht verandering in brengen. Wie de geschiedenis van de relatie tussen geloof en wetenschap in duikt, komt tot verrassende inzichten. De moderne mens leeft met veel stereotypen die historisch niet verantwoord blijken te zijn. Afgezaagde typeringen als ‘Vroeger dachten we dat de
Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en satisfied 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
We use nanofabricated microfluidic buildings to sample spatial boundaries for micro organism and biomimetic vesicles with reconstituted protein networks which assess the fundamental function of spatial confinement in the molecular and cellular level. Our jobs involve the subsequent:
Dynamic ParB–DNA interactions initiate and sustain a partition condensate for bacterial chromosome segregation
The rotors harness Vitality from a nanoscale h2o and ion movement that's created by a static chemical or electrochemical probable gradient inside the nanopore, that are founded by way of a salt gradient or applied voltage, respectively. These synthetic nanoengines self-organize and work autonomously in physiological problems, suggesting tips on how to setting up Power-transducing motors at nanoscale interfaces.
There was a single difficulty although — we did not notice any measurable electrical conduction from The one polymer molecules. We concluded that at The only-molecule degree, conducting polymers were actually not such terrific conductors, which was alternatively disappointing. We Consequently broadened our look at to try to locate more promising molecules.
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
1999, initial measurement on the wavefunction of one molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive proof to get a new Luttinger description of interacting electrons in nanotubes
2005, discovery of your mechanism of DNA uncoiling by topoisomerase enzymes; discovery of long-array conformational improvements in Mre11/DNA restore complexes; and initially pressure ceesdekker.net measurements on a DNA molecule in a very nanopore
Eventually, I'll briefly sketch many of our Thoughts to explore the developing of synthetic cells, exclusively our initially ways to determine artificial cell division.